Automatic Control of Dissolved Oxygen Concentration in Stirred Microbial Cultures
نویسندگان
چکیده
منابع مشابه
Control of Dissolved Oxygen in Stirred Bioreactors
This report discusses control of dissolved oxygen in a bioreactor where the oxygen supply is manipulated using the stirrer speed. In batch and fed-batch cultivations the operating conditions change significantly which may cause tuning problems. Analysis using a linearized process model shows that the process dynamics is mainly affected by changes in the volumetric oxygen transfer coefficient KL...
متن کاملMeasuring Dissolved Oxygen Concentration in Aquaculture
(DO) is considered the most important water quality variable in fish culture. In the broadest sense, however, dissolved oxygen concentration is no more important than other environmental variables because any factor that is outside the range tolerated by fish can cause stress or death. What makes dissolved oxygen concentration so important in intensive fish culture is the speed with which it ca...
متن کاملApplication of Gene Expression Programming to water dissolved oxygen concentration prediction
This research based on record and collected data from four stations at Eymir Lake, Turkey, which are monitored daily in seven months. Water quality monitoring using former methods are time-needed and expensive, while the application of gene expression programming is more understandable, rapid, and reliable which is used in this article to provide a prediction for dissolved oxygen. The concentra...
متن کاملInfluence of aeration-homogenization system in stirred tank bioreactors, dissolved oxygen concentration and pH control mode on BHK-21 cell growth and metabolism.
This work focused on determining the effect of dissolved oxygen concentration (DO) on growth and metabolism of BHK-21 cell line (host cell for recombinant proteins manufacturing and viral vaccines) cultured in two stirred tank bioreactors with different aeration-homogenization systems, as well as pH control mode. BHK-21 cell line adapted to single-cell suspension was cultured in Celligen withou...
متن کاملSimulation of Feedforward-Feedback Control of Dissolved Oxygen (DO) of Microbial Repeated Fed-batch Culture
Fed-batch culture is often used in industry, and dissolved oxygen (DO) concentration control is important in fermentation process control. DO control is often applied by using feedback (FB) control strategy. But, feedforward-feedback (FFFB) control has the advantage in dealing with the time-varying characteristics resulting from cell growth during the fermentation process. Mathematical modeling...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of General Microbiology
سال: 1966
ISSN: 0022-1287
DOI: 10.1099/00221287-45-2-289